1 milligram for 550 EURO !! IST-9 mAb reacts both with sections from frozen and paraformaldehyde fixed tissues. IST-9 reacts with the C’-C’ loop of ED-A preventing ED-A binding with integrins alpha5-beta1, alpha4-beta1 and alpha9-beta1. IST-9 inhibits fibroblasts differentiation into myo-fibroblasts and TGF-beta activation, thus inhibiting fibrosis (see under the Antibodies section). More recently it has […]